Can your lube affect your chances of getting pregnant? Yes some lubricants can make it harder for sperm to reach the egg. Look for sperm safe or fertility friendly formulas that mimic your The most pregnancy friendly lubricants are the water based kinds. These lubes are water soluble, which means they dissolve in water. They're safer for you and your baby, typically because they contain fewer chemicals than Are lubricants OK if trying to get pregnant? MadeForMums Can You Use Lube During Pregnancy? Chiavaye Anal sex is often seen as low risk, especially when pregnancy isn't the concern. But medically speaking, safety isn't decided by just one outcome. The anus and vagina are very different parts