Car Vibrating? These 5 Reasons Could Be Why, ., 1 Wheel Imbalance, Uneven weight distribution causes vibration at certain speeds, Fix: Wheel balancing, ., 2 Tyre Issues, Worn out or uneven If your truck is vibrating, dont ignore the tire wear pattern. Uneven tires can absolutely cause vibration especially at highway speeds. When tread wears inconsistently, you get: Irregular tire Causes of Tire Vibration Can Over Inflated Tires Cause Vibration Why is My Car Vibrating? MOOG Parts